London Researcher Dr. Shawn Li Receives CCS Innovation Grant to Study Ways to Overcome Chemotherapy Resistance in Breast Cancer

Dr. Shawn Li has received a CCS Innovation Grant to study ways to overcome chemotherapy resistance in breast cancer. The focus of Dr. Li’s work is the “triple negative” cancer cell that test negative for three things: estrogen receptors, progesterone receptors and HER2 overexpression. Dr Li, a professor in the Department of Biochemistry at Western University, is studying a biochemical reaction that plays a critical role in the death of triple-negative breast cancer cells and is also involved in chemotherapy resistance. His new project will study how two proteins –Numb and Set8—interact in this reaction and look for compounds that could serve as the first targeted treatments for triple-negative breast cancers.Read more.