Drs Mousumi Majumder and Peeyush K. Lala have found that an inflammation-associated enzyme called cyclo-oxygenase-2 (COX-2) expressed by about half of human breast cancer cases, drives tumour progression and spread to other tissues. It does this by influencing the inactivation of cancer fighting immune cells, stimulation of cancer cell movement and invasion of surrounding tissues, growth of new blood vessels, and circulation of cancer cells through the lymphatics (your body’s drainage system). Read more in this week’s Londoner.